BAIT
SIX1
BOS3, DFNA23, TIP39
SIX homeobox 1
GO Process (26)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- branching involved in ureteric bud morphogenesis [ISS]
- embryonic cranial skeleton morphogenesis [ISS]
- embryonic skeletal system morphogenesis [ISS]
- epithelial cell differentiation [ISS]
- generation of neurons [ISS]
- inner ear development [ISS]
- inner ear morphogenesis [ISS]
- kidney development [ISS]
- mesonephric tubule formation [ISS]
- metanephric mesenchyme development [ISS]
- myoblast migration [ISS]
- negative regulation of neuron apoptotic process [ISS]
- organ induction [ISS]
- pattern specification process [ISS]
- positive regulation of branching involved in ureteric bud morphogenesis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription, DNA-templated [ISS]
- positive regulation of ureteric bud formation [ISS]
- protein localization to nucleus [IDA]
- regulation of branch elongation involved in ureteric bud branching [ISS]
- regulation of neuron differentiation [ISS]
- regulation of transcription, DNA-templated [ISS]
- skeletal muscle tissue development [ISS]
- thymus development [ISS]
- thyroid gland development [ISS]
- ureteric bud development [ISS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISS]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISS]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
VTN
V75, VN, VNT
vitronectin
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- cell adhesion [TAS]
- cell adhesion mediated by integrin [IDA]
- cell-matrix adhesion [IDA]
- endodermal cell differentiation [IDA]
- extracellular matrix organization [TAS]
- immune response [TAS]
- innate immune response [TAS]
- negative regulation of blood coagulation [IC]
- negative regulation of endopeptidase activity [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of protein binding [IDA]
- positive regulation of receptor-mediated endocytosis [IDA]
- positive regulation of smooth muscle cell migration [IDA]
- positive regulation of vascular endothelial growth factor receptor signaling pathway [TAS]
- positive regulation of wound healing [IC]
- regulation of complement activation [TAS]
- smooth muscle cell-matrix adhesion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID