BAIT
STAT3
ADMIO, APRF, HIES
signal transducer and activator of transcription 3 (acute-phase response factor)
GO Process (27)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
- JAK-STAT cascade [TAS]
- JAK-STAT cascade involved in growth hormone signaling pathway [IDA, ISS, TAS]
- astrocyte differentiation [ISS]
- cellular component movement [TAS]
- cellular response to hormone stimulus [IDA]
- cytokine-mediated signaling pathway [NAS]
- eating behavior [ISS]
- eye photoreceptor cell differentiation [ISS]
- glucose homeostasis [ISS]
- growth hormone receptor signaling pathway [IDA]
- interleukin-6-mediated signaling pathway [IDA]
- intracellular receptor signaling pathway [IDA]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- nervous system development [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphorylation [ISS]
- positive regulation of Notch signaling pathway [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- protein import into nucleus [IDA]
- radial glial cell differentiation [ISS]
- regulation of transcription from RNA polymerase II promoter [ISS]
- regulation of transcription, DNA-templated [IDA]
- response to estradiol [IDA]
- sexual reproduction [ISS]
- signal transduction [TAS]
- temperature homeostasis [ISS]
Gene Ontology Molecular Function- DNA binding [ISS]
- RNA polymerase II repressing transcription factor binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- protein binding [IPI]
- protein dimerization activity [ISS]
- protein kinase binding [ISS]
- protein phosphatase binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- DNA binding [ISS]
- RNA polymerase II repressing transcription factor binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- protein binding [IPI]
- protein dimerization activity [ISS]
- protein kinase binding [ISS]
- protein phosphatase binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
Homo sapiens
PREY
ZFPM2
DIH3, FOG2, SRXY9, ZC2HC11B, ZNF89B, hFOG-2
zinc finger protein, FOG family member 2
GO Process (8)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- blood coagulation [TAS]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IBA]
- negative regulation of transcription, DNA-templated [IDA]
- outflow tract septum morphogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- right ventricular cardiac muscle tissue morphogenesis [IMP]
- ventricular septum morphogenesis [IMP]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA]
- RNA polymerase II transcription coactivator activity [NAS]
- RNA polymerase II transcription factor binding [IBA]
- protein binding [IPI]
- transcription corepressor activity [IDA]
- transcription factor binding [IPI]
- zinc ion binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IBA]
- RNA polymerase II transcription coactivator activity [NAS]
- RNA polymerase II transcription factor binding [IBA]
- protein binding [IPI]
- transcription corepressor activity [IDA]
- transcription factor binding [IPI]
- zinc ion binding [NAS]
Gene Ontology Cellular Component
- nucleoplasm [TAS]
- nucleus [IBA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID