AURKB
Gene Ontology Biological Process
- cellular response to UV [ISO]
- cleavage furrow formation [ISO]
- histone H3-S28 phosphorylation [IDA]
- mitotic spindle midzone assembly [ISO]
- mitotic spindle organization [IBA]
- negative regulation of B cell apoptotic process [ISO]
- negative regulation of protein binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cytokinesis [ISO]
- protein localization to kinetochore [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of cytokinesis [IBA]
- spindle stabilization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- chromocenter [IDA]
- chromosome passenger complex [IDA, ISO]
- condensed chromosome, centromeric region [ISO]
- condensed nuclear chromosome, centromeric region [IBA, ISO]
- kinetochore [ISO]
- midbody [IDA, ISO]
- mitotic spindle pole [ISO]
- nucleus [ISO]
- spindle [ISO]
- spindle microtubule [IBA]
- spindle midzone [IBA]
- spindle pole centrosome [IBA]
BMI1
Gene Ontology Biological Process
- DNA methylation [IMP]
- brain development [IMP]
- cellular process [TAS]
- embryonic skeletal system development [IGI]
- embryonic skeletal system morphogenesis [IGI]
- histone acetylation [IGI]
- histone ubiquitination [IDA]
- humoral immune response [IMP]
- in utero embryonic development [IGI]
- negative regulation of apoptotic signaling pathway [IGI]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- positive regulation of B cell proliferation [IMP]
- positive regulation of immature T cell proliferation in thymus [IMP]
- regulation of catalytic activity [IDA]
- rostrocaudal neural tube patterning [IMP]
- skeletal system development [IMP]
- somatic stem cell division [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes.
Reversible cellular quiescence is critical for developmental processes in metazoan organisms and is characterized by a reduction in cell size and transcriptional activity. We show that the Aurora B kinase and the polycomb protein Ring1B have essential roles in regulating transcriptionally active genes in quiescent lymphocytes. Ring1B and Aurora B bind to a wide range of active promoters in resting ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID