GNA11
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SLC9A3R1
Gene Ontology Biological Process
- bile acid secretion [ISS]
- glutathione transport [ISS]
- microvillus assembly [IMP]
- negative regulation of ERK1 and ERK2 cascade [IDA]
- negative regulation of cell proliferation [IDA, IMP]
- negative regulation of phosphatidylinositol 3-kinase signaling [ISS]
- negative regulation of platelet-derived growth factor receptor signaling pathway [ISS]
- negative regulation of protein kinase B signaling [IMP]
- positive regulation of intrinsic apoptotic signaling pathway [IDA]
- protein complex assembly [TAS]
- regulation of protein kinase activity [ISS]
- regulation of sodium:proton antiporter activity [NAS]
- renal absorption [ISS]
- renal phosphate ion absorption [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50).
Although ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is a PDZ domain-containing protein known to bind to various channels, receptors, cytoskeletal elements, and cytoplasmic proteins, there is still very little evidence for a role of EBP50 in the regulation of receptor signal transduction. In this report, we show that EBP50 inhibits the phospholipase C (PLC)-beta-mediated inositol phosphate production of a Galpha(q)-coupled receptor as ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GNA11 SLC9A3R1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | 904276 | |
| SLC9A3R1 GNA11 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | 904277 |
Curated By
- BioGRID