PREY

PCNT

KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4
pericentrin
Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

Tsang WY, Spektor A, Luciano DJ, Indjeian VB, Chen Z, Salisbury JL, Sanchez I, Dynlacht BD

The centrosome is an integral component of the eukaryotic cell cycle machinery, yet very few centrosomal proteins have been fully characterized to date. We have undertaken a series of biochemical and RNA interference (RNAi) studies to elucidate a role for CP110 in the centrosome cycle. Using a combination of yeast two-hybrid screens and biochemical analyses, we report that CP110 interacts ... [more]

Mol. Biol. Cell Aug. 01, 2006; 17(8);3423-34 [Pubmed: 16760425]

Throughput

  • Low Throughput

Ontology Terms

  • hek-293t cell (BTO:0002181)

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PCNT AKAP9
Proximity Label-MS
Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

High29.75BioGRID
2998988

Curated By

  • BioGRID