BAIT
FOR3
SPCC895.05
formin For3
GO Process (9)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- actin filament bundle assembly [IMP]
- actin filament organization [IMP]
- actin nucleation [ISM]
- activation of bipolar cell growth [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic actomyosin contractile ring assembly [IGI]
- protein localization to actin cytoskeleton [IMP]
- regulation of filamentous growth [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
RLC1
SPAC926.03
myosin II regulatory light chain Rlc1
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
The formins Cdc12 and For3 cooperate during contractile ring assembly in cytokinesis.
Both de novo-assembled actin filaments at the division site and existing filaments recruited by directional cortical transport contribute to contractile ring formation during cytokinesis. However, it is unknown which source is more important. Here, we show that fission yeast formin For3 is responsible for node condensation into clumps in the absence of formin Cdc12. For3 localization at the division site ... [more]
J. Cell Biol. Oct. 14, 2013; 203(1);101-14 [Pubmed: 24127216]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID