ZNF24
Gene Ontology Biological Process
Gene Ontology Molecular Function
HMGB1
Gene Ontology Biological Process
- DNA ligation involved in DNA repair [ISS]
- DNA recombination [ISS]
- DNA topological change [ISS]
- V(D)J recombination [IDA]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- base-excision repair, DNA ligation [IDA]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- chromatin remodeling [IBA]
- dendritic cell chemotaxis [ISS]
- inflammatory response to antigenic stimulus [IEP]
- innate immune response [TAS]
- myeloid dendritic cell activation [ISS]
- negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- neuron projection development [ISS]
- positive chemotaxis [ISS]
- positive regulation of DNA binding [IDA]
- positive regulation of apoptotic process [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding, bending [IMP, ISS]
- RAGE receptor binding [ISS]
- chemoattractant activity [ISS]
- chromatin binding [IBA]
- cytokine activity [ISS]
- damaged DNA binding [ISS]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription factor binding [IPI]
- DNA binding, bending [IMP, ISS]
- RAGE receptor binding [ISS]
- chemoattractant activity [ISS]
- chromatin binding [IBA]
- cytokine activity [ISS]
- damaged DNA binding [ISS]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
A comprehensive resource of interacting protein regions for refining human transcription factor networks.
Large-scale data sets of protein-protein interactions (PPIs) are a valuable resource for mapping and analysis of the topological and dynamic features of interactome networks. The currently available large-scale PPI data sets only contain information on interaction partners. The data presented in this study also include the sequences involved in the interactions (i.e., the interacting regions, IRs) suggested to correspond to ... [more]
Throughput
- High Throughput
Additional Notes
- Protein-protein interactions detected between proteins translated in vitro
Curated By
- BioGRID