BAIT
NLK
nemo-like kinase
GO Process (8)
GO Function (9)
GO Component (3)
Gene Ontology Biological Process
- MAPK cascade [ISS]
- intracellular signal transduction [ISS]
- negative regulation of Wnt signaling pathway [ISS]
- peptidyl-threonine phosphorylation [ISS]
- protein phosphorylation [ISS]
- regulation of transcription, DNA-templated [ISS]
- serine phosphorylation of STAT3 protein [ISS]
- transforming growth factor beta receptor signaling pathway [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
KPNB1
IMB1, IPO1, IPOB, Impnb, NTF97
karyopherin (importin) beta 1
GO Process (12)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [TAS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cytokine-mediated signaling pathway [TAS]
- intracellular transport of virus [TAS]
- protein import into nucleus [IDA]
- protein import into nucleus, translocation [TAS]
- ribosomal protein import into nucleus [IDA]
- small molecule metabolic process [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interaction landscape of the human CMGC kinase group.
Cellular information processing via reversible protein phosphorylation requires tight control of the localization, activity, and substrate specificity of protein kinases, which to a large extent is accomplished by complex formation with other proteins. Despite their critical role in cellular regulation and pathogenesis, protein interaction information is available for only a subset of the 518 human protein kinases. Here we present ... [more]
Cell Rep Apr. 25, 2013; 3(4);1306-20 [Pubmed: 23602568]
Throughput
- High Throughput
Ontology Terms
- hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expresssion of bait
Curated By
- BioGRID