NLK
Gene Ontology Biological Process
- MAPK cascade [ISS]
- intracellular signal transduction [ISS]
- negative regulation of Wnt signaling pathway [ISS]
- peptidyl-threonine phosphorylation [ISS]
- protein phosphorylation [ISS]
- regulation of transcription, DNA-templated [ISS]
- serine phosphorylation of STAT3 protein [ISS]
- transforming growth factor beta receptor signaling pathway [IMP]
Gene Ontology Molecular Function
FAM222A
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interaction landscape of the human CMGC kinase group.
Cellular information processing via reversible protein phosphorylation requires tight control of the localization, activity, and substrate specificity of protein kinases, which to a large extent is accomplished by complex formation with other proteins. Despite their critical role in cellular regulation and pathogenesis, protein interaction information is available for only a subset of the 518 human protein kinases. Here we present ... [more]
Throughput
- High Throughput
Ontology Terms
- hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expresssion of bait
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FAM222A NLK | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9637 | BioGRID | 2249138 | |
| FAM222A NLK | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9992 | BioGRID | 3076391 | |
| FAM222A NLK | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3287474 |
Curated By
- BioGRID