BAIT
MAPK15
ERK7, ERK8
mitogen-activated protein kinase 15
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CACNA1H
CACNA1HB, Cav3.2, ECA6, EIG6
calcium channel, voltage-dependent, T type, alpha 1H subunit
GO Process (14)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- aldosterone biosynthetic process [IMP]
- axon guidance [TAS]
- calcium ion import [IDA]
- cellular response to hormone stimulus [IEP]
- cellular response to potassium ion [IEP]
- cortisol biosynthetic process [IMP]
- membrane depolarization during action potential [IBA]
- muscle contraction [TAS]
- muscle organ development [NAS]
- myoblast fusion [TAS]
- positive regulation of acrosome reaction [IMP]
- regulation of heart contraction [TAS]
- regulation of membrane potential [IDA]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interaction landscape of the human CMGC kinase group.
Cellular information processing via reversible protein phosphorylation requires tight control of the localization, activity, and substrate specificity of protein kinases, which to a large extent is accomplished by complex formation with other proteins. Despite their critical role in cellular regulation and pathogenesis, protein interaction information is available for only a subset of the 518 human protein kinases. Here we present ... [more]
Cell Rep Apr. 25, 2013; 3(4);1306-20 [Pubmed: 23602568]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expresssion of bait
Curated By
- BioGRID