BAIT
KATNA1
katanin p60 (ATPase-containing) subunit A1
GO Process (9)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
- ATP catabolic process [IBA, ISO, TAS]
- cytoplasmic microtubule organization [IBA, ISO]
- microtubule bundle formation [ISO]
- microtubule severing [IDA, ISO]
- mitotic nuclear division [TAS]
- negative regulation of neuron projection development [IDA]
- neuron migration [ISO]
- protein localization [ISO, TAS]
- protein ubiquitination [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
TCP1
CCTalpha, Tcp-1
t-complex 1
GO Process (6)
GO Function (2)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- acrosomal vesicle [ISO]
- cell body [ISO]
- centrosome [ISO]
- chaperonin-containing T-complex [ISO]
- extracellular vesicular exosome [ISO]
- heterochromatin [IDA]
- microtubule [ISO]
- microtubule organizing center [ISO]
- myelin sheath [ISO]
- nuclear heterochromatin [ISO]
- pericentriolar material [ISO]
- zona pellucida receptor complex [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
USP47 and C terminus of Hsp70-interacting protein (CHIP) antagonistically regulate katanin-p60-mediated axonal growth.
Katanin is a heterodimeric enzyme that severs and disassembles microtubules. While the p60 subunit has the enzyme activity, the p80 subunit regulates the p60 activity. The microtubule-severing activity of katanin plays an essential role in axonal growth. However, the mechanisms by which neuronal cells regulate the expression of katanin-p60 remains unknown. Here we showed that USP47 and C terminus of ... [more]
J. Neurosci. Jul. 31, 2013; 33(31);12728-38 [Pubmed: 23904609]
Throughput
- Low Throughput
Curated By
- BioGRID