BAIT
AMPH
amphiphysin
GO Process (2)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DNM2
Dyn2, Udnm, b2b2159Clo
dynamin 2
GO Process (6)
GO Function (4)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- cell junction [ISO]
- clathrin-coated endocytic vesicle [ISO]
- coated pit [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- growth cone [ISO]
- microtubule [ISO]
- nucleus [ISO]
- photoreceptor inner segment [IDA]
- postsynaptic membrane [ISO]
- protein complex [ISO]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis.
The GLUT4 glucose transporter continuously recycles between the cell surface and an endosomal compartment in adipocytes. Insulin decreases the rate of GLUT4 endocytosis in addition to increasing its exocytosis. Endocytosis of the transporter is thought to occur at least in part via the clathrin-mediated endocytic system. The protein dynamin is involved in the final stages of clathrin-coated vesicle formation. Here ... [more]
J. Biol. Chem. Apr. 03, 1998; 273(14);8169-76 [Pubmed: 9525921]
Throughput
- Low Throughput
Curated By
- BioGRID