BAIT

GNB2L1

Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1, HLC7
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GO Process (24)
GO Function (13)
GO Component (11)
Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1.

Marques N, Sese M, Canovas V, Valente F, Bermudo R, de Torres I, Fernandez Y, Abasolo I, Fernandez PL, Contreras H, Castellon E, Celia-Terrassa T, Mendez R, Ramon Y Cajal S, Thomson TM, Paciucci R

Prostate tumor overexpressed-1 (PTOV1), a modulator of the Mediator transcriptional regulatory complex, is expressed at high levels in prostate cancer and other neoplasias in association with a more aggressive disease. Here we show that PTOV1 interacts directly with receptor of activated protein C kinase 1 (RACK1), a regulator of protein kinase C and Jun signaling and also a component of ... [more]

Oncogene Mar. 04, 2013; 0(0); [Pubmed: 23455324]

Throughput

  • Low Throughput

Ontology Terms

  • cell line: pc-3 cell (BTO:0001061) [prostate adenocarcinoma (DOID:2526)]

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
GNB2L1 RPS6
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
3365996

Curated By

  • BioGRID