BAIT

CUT3

smc4, SPBC146.03c
condensin complex subunit Cut3
GO Process (3)
GO Function (1)
GO Component (5)
Schizosaccharomyces pombe (972h)
PREY

SNF21

SPAC29A4.21, brg1, SPAC1250.01
ATP-dependent DNA helicase Snf21
Schizosaccharomyces pombe (972h)

Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Publication

A Genetic Screen for Functional Partners of Condensin in Fission Yeast.

Robellet X, Fauque L, Legros P, Mollereau E, Janczarski S, Parrinello H, Desvignes JP, Thevenin M, Bernard P

Mitotic chromosome condensation is a pre-requisite for the accurate segregation of chromosomes during cell division, and the conserved condensin complex a central player of this process. However, how condensin binds chromatin and shapes mitotic chromosomes remain poorly understood. Recent genome-wide binding studies showing that in most species condensin is enriched near highly expressed genes suggest a conserved link between condensin ... [more]

G3 (Bethesda) Dec. 20, 2013; 0(0); [Pubmed: 24362309]

Throughput

  • Low Throughput

Ontology Terms

  • phenotype: inviable (APO:0000112)

Additional Notes

  • cut3-477 allele; 32 deg C.

Curated By

  • BioGRID