Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.

Liu T, Wan L, Wu Y, Chen J, Huang J

The Shu complex in yeast plays an important role in the homologous recombination pathway, which is critical for the maintenance of genomic integrity. The identification of human SWS1 (hSWS1) as the homolog of budding yeast Shu2 implicated that the Shu complex is evolutionarily conserved. However, the human counterparts of other components in this complex have not yet been identified and ... [more]

J. Biol. Chem. Dec. 02, 2011; 286(48);41758-66 [Pubmed: 21965664]

Throughput

  • Low Throughput

Curated By

  • BioGRID