BAIT
ZSWIM7
SWS1
zinc finger, SWIM-type containing 7
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
XRCC3
CMM6
X-ray repair complementing defective repair in Chinese hamster cells 3
GO Process (8)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IMP]
- DNA recombination [TAS]
- DNA repair [IGI]
- cellular response to DNA damage stimulus [TAS]
- double-strand break repair via homologous recombination [IMP]
- positive regulation of mitotic cell cycle spindle assembly checkpoint [IMP]
- regulation of centrosome duplication [IMP]
- resolution of mitotic recombination intermediates [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.
The Shu complex in yeast plays an important role in the homologous recombination pathway, which is critical for the maintenance of genomic integrity. The identification of human SWS1 (hSWS1) as the homolog of budding yeast Shu2 implicated that the Shu complex is evolutionarily conserved. However, the human counterparts of other components in this complex have not yet been identified and ... [more]
J. Biol. Chem. Dec. 02, 2011; 286(48);41758-66 [Pubmed: 21965664]
Throughput
- Low Throughput
Curated By
- BioGRID