BAIT

GNB4

CMTD1F, RP11-145M9.4
guanine nucleotide binding protein (G protein), beta polypeptide 4
GO Process (4)
GO Function (1)
GO Component (3)
Homo sapiens
PREY

GNG3

guanine nucleotide binding protein (G protein), gamma 3
GO Process (6)
GO Function (1)
GO Component (1)
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.

Rosskopf D, Nikula C, Manthey I, Joisten M, Frey U, Kohnen S, Siffert W

The aim of this study was the characterization of the human Gbeta4 subunit of heterotrimeric G proteins. Human Gbeta4 is widely expressed. Its gene is located on chromosome 3 with a genomic structure indistinguishable from that of the genes of Gbeta1 to Gbeta3, but entirely different from Gbeta5. In vitro translation co-precipitation analyses revealed that Gbeta4 can form stable dimers ... [more]

FEBS Lett. Jun. 05, 2003; 544(1);27-32 [Pubmed: 12782285]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
GNG3 GNB4
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High1BioGRID
2225056
GNG3 GNB4
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High0.9997BioGRID
3066523
GNG3 GNB4
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID