Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

A new member of the amphiphysin family connecting endocytosis and signal transduction pathways.

Leprince C, Romero F, Cussac D, Vayssiere B, Berger R, Tavitian A, Camonis JH

Src homology 3 (SH3) domains are conserved modules which participate in protein interaction by recognizing proline-rich motifs on target molecules. To identify new SH3-containing proteins, we performed a two-hybrid screen with a proline-rich region of human SOS-1. One of the specific SOS-1 interacting clones that were isolated from a mouse brain cDNA library defines a new protein that was named ... [more]

J. Biol. Chem. Jun. 13, 1997; 272(24);15101-5 [Pubmed: 9182529]

Throughput

  • Low Throughput

Curated By

  • BioGRID