BAIT
BIN1
AMPH2, AMPHL, SH3P9
bridging integrator 1
GO Process (6)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AP2A1
ADTAA, AP2-ALPHA, CLAPA1
adaptor-related protein complex 2, alpha 1 subunit
GO Process (13)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- Golgi to endosome transport [NAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- axon guidance [TAS]
- clathrin-mediated endocytosis [TAS]
- endocytosis [NAS]
- epidermal growth factor receptor signaling pathway [TAS]
- intracellular protein transport [NAS]
- negative regulation of epidermal growth factor receptor signaling pathway [TAS]
- negative regulation of hyaluronan biosynthetic process [IDA, IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- regulation of defense response to virus by virus [TAS]
- synaptic transmission [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
A new member of the amphiphysin family connecting endocytosis and signal transduction pathways.
Src homology 3 (SH3) domains are conserved modules which participate in protein interaction by recognizing proline-rich motifs on target molecules. To identify new SH3-containing proteins, we performed a two-hybrid screen with a proline-rich region of human SOS-1. One of the specific SOS-1 interacting clones that were isolated from a mouse brain cDNA library defines a new protein that was named ... [more]
J. Biol. Chem. Jun. 13, 1997; 272(24);15101-5 [Pubmed: 9182529]
Throughput
- Low Throughput
Curated By
- BioGRID