NR3C1
Gene Ontology Biological Process
- adrenal gland development [ISO]
- aging [IEP]
- androgen metabolic process [IEP]
- brain development [IEP]
- cellular response to dexamethasone stimulus [IMP]
- cellular response to magnesium ion [IEP]
- cellular response to steroid hormone stimulus [ISO, ISS]
- chromatin remodeling [IMP]
- chromatin-mediated maintenance of transcription [IMP]
- circadian rhythm [IEP]
- glucocorticoid mediated signaling pathway [ISO]
- glucocorticoid metabolic process [ISO]
- glucocorticoid receptor signaling pathway [ISO]
- lung development [IEP]
- mammary gland duct morphogenesis [ISO]
- maternal behavior [ISO]
- muscle atrophy [IEP]
- negative regulation of glucocorticoid mediated signaling pathway [ISO]
- negative regulation of synaptic plasticity [IMP]
- negative regulation of vascular permeability [IMP]
- positive regulation of cell growth involved in cardiac muscle cell development [IMP]
- positive regulation of dendritic spine development [IMP]
- positive regulation of glucocorticoid receptor signaling pathway [IDA]
- positive regulation of glutamate secretion [IMP]
- positive regulation of neuron apoptotic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- regulation of cell proliferation [IDA]
- regulation of glucocorticoid biosynthetic process [ISO]
- regulation of gluconeogenesis [ISO]
- regulation of glucose metabolic process [IMP]
- regulation of transcription, DNA-templated [ISO]
- response to activity [IEP]
- response to arsenic-containing substance [IDA]
- response to calcium ion [IEP]
- response to corticosterone [IEP]
- response to dexamethasone [IEP]
- response to electrical stimulus [IEP]
- response to inactivity [IEP]
- response to insulin [IEP]
- response to mercury ion [IEP]
- response to radiation [IEP]
Gene Ontology Molecular Function- DNA binding [ISO]
- Hsp70 protein binding [IDA]
- Hsp90 protein binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II regulatory region DNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [IDA]
- glucocorticoid receptor activity [ISO]
- glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity [ISO, ISS]
- heat shock protein binding [IDA]
- hormone binding [IPI]
- protein binding [IPI]
- protein complex binding [IDA, IPI]
- protein dimerization activity [ISO, TAS]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- receptor tyrosine kinase binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO, ISS]
- steroid binding [IPI, ISO]
- steroid hormone binding [ISO, ISS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- zinc ion binding [TAS]
- DNA binding [ISO]
- Hsp70 protein binding [IDA]
- Hsp90 protein binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II regulatory region DNA binding [IDA]
- chromatin binding [IDA]
- double-stranded DNA binding [IDA]
- glucocorticoid receptor activity [ISO]
- glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity [ISO, ISS]
- heat shock protein binding [IDA]
- hormone binding [IPI]
- protein binding [IPI]
- protein complex binding [IDA, IPI]
- protein dimerization activity [ISO, TAS]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- receptor tyrosine kinase binding [IPI]
- sequence-specific DNA binding [IDA, ISO]
- sequence-specific DNA binding transcription factor activity [IMP, ISO, ISS]
- steroid binding [IPI, ISO]
- steroid hormone binding [ISO, ISS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- zinc ion binding [TAS]
Gene Ontology Cellular Component
UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Lose dose genistein inhibits glucocorticoid receptor and ischemic brain injury in female rats.
Although acute bolus of genistein treatment has been shown to protect against neuronal damage in experimental brain injury animal models, chronic continuous low dose treatment of genistein on ischemic brain injury has not been well elucidated. In the present study, female rats were received either pure genistein (0.1mg/kg/day via osmotic minipumps) or placebo at the time of ovariectomy, and transient ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID