BAIT

RANBP9

BPM-L, BPM90, RANBPM, RanBP7
RAN binding protein 9
GO Process (3)
GO Function (3)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Enhancement of transactivation activity of Rta of Epstein-Barr virus by RanBPM.

Chang LK, Liu ST, Kuo CW, Wang WH, Chuang JY, Bianchi E, Hong YR

Epstein-Barr virus (EBV) expresses the immediate-early protein Rta to activate the transcription of EBV lytic genes and the lytic cycle. We show that RanBPM acts as a binding partner of Rta in yeast two-hybrid analysis. The binding was confirmed by glutathione-S-transferase pull-down assay. A coimmunoprecipitation experiment and confocal microscopy revealed that RanBPM and Rta interact in vivo and colocalize in ... [more]

J. Mol. Biol. May. 30, 2008; 379(2);231-42 [Pubmed: 18455188]

Throughput

  • Low Throughput

Curated By

  • BioGRID