ATG4A
Gene Ontology Biological Process
Gene Ontology Molecular Function
GABARAPL2
Gene Ontology Biological Process
- autophagic vacuole assembly [IBA]
- autophagy [NAS]
- cellular response to nitrogen starvation [IBA]
- intra-Golgi vesicle-mediated transport [ISS]
- membrane fusion [IBA]
- mitochondrion degradation [IBA]
- negative regulation of proteasomal protein catabolic process [IMP]
- nucleophagy [IBA]
- positive regulation of ATPase activity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Proteolytic Processing)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A.
Docking of a vesicle at the appropriate target membrane involves an interaction between integral membrane proteins located on the vesicle (v-SNAREs) and those located on the target membrane (t-SNAREs). GATE-16 (Golgi-associated ATPase enhancer of 16 kDa) was shown to modulate the activity of SNAREs in the Golgi apparatus and is therefore an essential component of intra-Golgi transport and post-mitotic Golgi ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID