BAIT
ASB3
ASB-3
ankyrin repeat and SOCS box containing 3
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
EPB41L3
4.1B, DAL-1, DAL1
erythrocyte membrane protein band 4.1-like 3
GO Process (9)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- cortical cytoskeleton organization [TAS]
- cytoskeletal anchoring at plasma membrane [TAS]
- myelin maintenance [ISS]
- neuron projection morphogenesis [ISS]
- paranodal junction assembly [ISS]
- protein localization to juxtaparanode region of axon [ISS]
- protein localization to paranode region of axon [ISS]
- protein localization to plasma membrane [ISS]
- regulation of cell shape [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.
The ankyrin and SOCS (suppressor of cytokine signaling) box (ASB) family of proteins function as the substrate recognition subunit in a subset of Elongin-Cullin-SOCS (ECS) E3 ubiquitin ligases. Despite counting 18 members in humans, the identity of the physiological targets of the Asb proteins remains largely unexplored. To increase our understanding of the function of ASB proteins, we conducted a ... [more]
J. Biol. Chem. Jan. 24, 2014; 289(4);2043-54 [Pubmed: 24337577]
Throughput
- High Throughput
Curated By
- BioGRID