ASB10
AP1G1
Gene Ontology Biological Process
- Golgi to lysosome transport [IMP]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- endosome to melanosome transport [IMP]
- melanosome organization [IC]
- membrane organization [TAS]
- positive regulation of natural killer cell degranulation [IMP]
- positive regulation of natural killer cell mediated cytotoxicity [IMP]
- post-Golgi vesicle-mediated transport [TAS]
- regulation of defense response to virus by virus [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- AP-type membrane coat adaptor complex [TAS]
- Golgi apparatus [IDA]
- Golgi membrane [TAS]
- clathrin-coated vesicle [IDA]
- clathrin-coated vesicle membrane [ISS]
- cytoplasm [IDA]
- cytoplasmic vesicle membrane [TAS]
- cytosol [TAS]
- intracellular membrane-bounded organelle [IDA]
- lysosomal membrane [TAS]
- membrane [IDA]
- recycling endosome [IDA]
- trans-Golgi network membrane [TAS]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.
The ankyrin and SOCS (suppressor of cytokine signaling) box (ASB) family of proteins function as the substrate recognition subunit in a subset of Elongin-Cullin-SOCS (ECS) E3 ubiquitin ligases. Despite counting 18 members in humans, the identity of the physiological targets of the Asb proteins remains largely unexplored. To increase our understanding of the function of ASB proteins, we conducted a ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ASB10 AP1G1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.3886 | BioGRID | 3243863 |
Curated By
- BioGRID