BAIT
MIB1
cg5841, chunp6889, fe47f05, im:7148100, mib, wu:fe47f05
mindbomb E3 ubiquitin protein ligase 1
GO Process (45)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- Notch signaling pathway [IMP]
- blood vessel development [IMP]
- blood vessel morphogenesis [IMP]
- brain development [IMP]
- determination of left/right symmetry [IMP]
- diencephalon development [IMP]
- digestive tract morphogenesis [IMP]
- embryonic camera-type eye development [IMP]
- embryonic pattern specification [IMP]
- endothelial cell development [IMP]
- epithelial cell development [IMP]
- floor plate formation [IMP]
- generation of neurons [IMP]
- glial cell differentiation [IMP]
- habenula development [IMP]
- hair cell differentiation [IMP]
- heart development [IMP]
- hematopoietic stem cell differentiation [IMP]
- hemopoiesis [IMP]
- hindbrain development [IMP]
- inner ear receptor cell differentiation [IMP]
- melanocyte differentiation [IMP]
- neuron differentiation [IMP]
- neuron fate commitment [IMP]
- otic vesicle development [IMP]
- positive regulation of Notch signaling pathway [IMP]
- positive regulation of cell proliferation [IGI]
- positive regulation of protein ubiquitination [IPI]
- pronephros development [IMP]
- protein autoubiquitination [IDA, IMP]
- protein ubiquitination [IDA]
- regulation of Notch signaling pathway [IMP]
- regulation of glial cell differentiation [IMP]
- regulation of neuron differentiation [IMP]
- regulation of receptor internalization [IDA]
- regulation of receptor-mediated endocytosis [IMP]
- rhombomere boundary formation [IMP]
- somitogenesis [IMP]
- spinal cord association neuron specification [IMP]
- spinal cord development [IMP]
- spinal cord motor neuron cell fate specification [IMP]
- taste bud formation [IMP]
- vasculogenesis [IMP]
- ventral spinal cord interneuron differentiation [IMP]
- ventral spinal cord interneuron specification [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Danio rerio
PREY
FAM76B
fa11h02, wu:fa11h02, zgc:73333, DKEY-110K5.1
family with sequence similarity 76, member B
GO Process (0)
GO Function (0)
GO Component (0)
Danio rerio
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.
Notch signaling pathway defines an evolutionarily conserved mechanism in cell-fate determination in a broad spectrum of developmental processes through local cell interactions. mind bomb (mib) encodes an E3 ubiquitin ligase that is involved in Notch activation through Delta ubiquitylation and internalization. To further dissect the function of Mib, two yeast two-hybrid screens for zebrafish Mib/Mib2-binding proteins with different strategies have ... [more]
PLoS ONE Apr. 10, 2014; 9(4);e93394 [Pubmed: 24714733]
Throughput
- High Throughput
Curated By
- BioGRID