BAIT

MIB2

mindbomb E3 ubiquitin protein ligase 2
Danio rerio
PREY

ANKRD52A

ankrd52, zgc:112069
ankyrin repeat domain 52a
GO Process (0)
GO Function (0)
GO Component (0)
Danio rerio

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.

Tseng LC, Zhang C, Cheng CM, Xu H, Hsu CH, Jiang YJ

Notch signaling pathway defines an evolutionarily conserved mechanism in cell-fate determination in a broad spectrum of developmental processes through local cell interactions. mind bomb (mib) encodes an E3 ubiquitin ligase that is involved in Notch activation through Delta ubiquitylation and internalization. To further dissect the function of Mib, two yeast two-hybrid screens for zebrafish Mib/Mib2-binding proteins with different strategies have ... [more]

PLoS ONE Apr. 10, 2014; 9(4);e93394 [Pubmed: 24714733]

Throughput

  • High Throughput

Curated By

  • BioGRID