BAIT
RNF31
HOIP, ZIBRA
ring finger protein 31
GO Process (6)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFA8
CI-19KD, CI-PGIV, PGIV
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
GO Process (4)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling.
Linear ubiquitin chains are implicated in the regulation of the NF-κB pathway, immunity, and inflammation. They are synthesized by the LUBAC complex containing the catalytic subunit HOIL-1-interacting protein (HOIP) and are disassembled by the linear ubiquitin-specific deubiquitinase OTULIN. Little is known about the regulation of these opposing activities. Here we demonstrate that HOIP and OTULIN interact and act as a ... [more]
Mol. Cell Apr. 09, 2014; 0(0); [Pubmed: 24726327]
Throughput
- High Throughput
Curated By
- BioGRID