BAIT
ADARB1
ADAR2, DRABA2, DRADA2, RED1
adenosine deaminase, RNA-specific, B1
GO Process (10)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- RNA processing [IDA]
- adenosine to inosine editing [IDA, TAS]
- base conversion or substitution editing [IC]
- gene expression [TAS]
- mRNA modification [TAS]
- negative regulation of cell migration [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [IDA]
- positive regulation of viral genome replication [IMP]
- regulation of cell cycle [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
IFRD2
IFNRP, SKMc15, SM15
interferon-related developmental regulator 2
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM65 regulates microRNA activity by ubiquitination of TNRC6.
MicroRNAs (miRNAs) are small evolutionarily conserved regulatory RNAs that modulate mRNA stability and translation in a wide range of cell types. MiRNAs are involved in a broad array of biological processes, including cellular proliferation, differentiation, and apoptosis. To identify previously unidentified regulators of miRNA, we initiated a systematic discovery-type proteomic analysis of the miRNA pathway interactome in human cells. Six ... [more]
Proc. Natl. Acad. Sci. U.S.A. May. 13, 2014; 111(19);6970-5 [Pubmed: 24778252]
Throughput
- High Throughput
Curated By
- BioGRID