BAIT

DGCR8

C22orf12, DGCRK6, Gy1, pasha, LP4941
DGCR8 microprocessor complex subunit
GO Process (2)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

PYCRL

pyrroline-5-carboxylate reductase-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

Li S, Wang L, Fu B, Berman MA, Diallo A, Dorf ME

MicroRNAs (miRNAs) are small evolutionarily conserved regulatory RNAs that modulate mRNA stability and translation in a wide range of cell types. MiRNAs are involved in a broad array of biological processes, including cellular proliferation, differentiation, and apoptosis. To identify previously unidentified regulators of miRNA, we initiated a systematic discovery-type proteomic analysis of the miRNA pathway interactome in human cells. Six ... [more]

Proc. Natl. Acad. Sci. U.S.A. May. 13, 2014; 111(19);6970-5 [Pubmed: 24778252]

Throughput

  • High Throughput

Curated By

  • BioGRID