BAIT
MSL1
MSL-1, hMSL1
male-specific lethal 1 homolog (Drosophila)
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
- MSL complex [IDA]
- nucleoplasm [IDA, TAS]
Homo sapiens
PREY
CDK9
C-2k, CDC2L4, CTK1, PITALRE, TAK, RP11-228B15.5
cyclin-dependent kinase 9
GO Process (16)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- cell proliferation [TAS]
- cellular response to cytokine stimulus [IDA]
- gene expression [TAS]
- negative regulation of cell cycle arrest [IDA]
- positive regulation of transcription from RNA polymerase II promoter [TAS]
- positive regulation of viral transcription [TAS]
- protein phosphorylation [IDA]
- regulation of DNA repair [IDA]
- regulation of histone modification [IDA]
- replication fork arrest [IDA]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
H2B Ubiquitylation Promotes RNA Pol II Processivity via PAF1 and pTEFb.
Histone H2B ubiquitination plays an important role in transcription regulation. It has been shown that H2B ubiquitination is regulated by multiple upstream events associated with elongating RNA polymerase. Here we demonstrate that H2B K34 ubiquitylation by the MOF-MSL complex is part of the protein networks involved in early steps of transcription elongation. Knocking down MSL2 in the MOF-MSL complex affects ... [more]
Mol. Cell May. 14, 2014; 0(0); [Pubmed: 24837678]
Throughput
- Low Throughput
Curated By
- BioGRID