BAIT
BACE1
C76936
beta-site APP cleaving enzyme 1
GO Process (3)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CMPK1
CK, CMK, CMPK, UMK, UMP-CMPK, UMPK, RP11-511I2.1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
GO Process (7)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- UMP biosynthetic process [TAS]
- nucleobase-containing small molecule interconversion [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- nucleoside diphosphate phosphorylation [IDA]
- nucleoside triphosphate biosynthetic process [IDA]
- pyrimidine ribonucleotide biosynthetic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin.
Using a yeast two-hybrid system, we screened a human brain cDNA library for possible interacting proteins with the C-terminal cytosolic tail of the beta-secretase beta-amyloid protein converting enzyme (BACE)1. This identified seven potential candidates, including the brain-specific type II membrane protein BRI3. Co-localization and co-immunoprecipitation experiments confirmed that BACE1 and BRI3 co-localize and interact with each other via the cytosolic ... [more]
J. Neurochem. Jan. 01, 2005; 92(1);93-102 [Pubmed: 15606899]
Throughput
- High Throughput
Curated By
- BioGRID