BAIT

XIRP2

CMYA3
xin actin-binding repeat containing 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

FLNC

ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4
filamin C, gamma
GO Process (1)
GO Function (3)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients.

Kley RA, Maerkens A, Leber Y, Theis V, Schreiner A, van der Ven PF, Uszkoreit J, Stephan C, Eulitz S, Euler N, Kirschner J, Mueller K, Meyer HE, Tegenthoff M, Fuerst DO, Vorgerd M, Mueller T, Marcus K

Filaminopathy is a subtype of myofibrillar myopathy caused by mutations in FLNC, the gene encoding filamin C, and histologically characterized by pathologic accumulation of several proteins within skeletal muscle fibers. With the aim to get new insights in aggregate composition, we collected aggregates and control tissue from skeletal muscle biopsies of six myofibrillar myopathy patients harboring three different FLNC mutations ... [more]

Mol. Cell Proteomics Jan. 01, 2013; 12(1);215-27 [Pubmed: 23115302]

Throughput

  • Low Throughput

Additional Notes

  • Figure 4

Curated By

  • BioGRID