CSNK2B
Gene Ontology Biological Process
- I-kappaB kinase/NF-kappaB signaling [TAS]
- adiponectin-activated signaling pathway [ISO]
- endothelial tube morphogenesis [ISO]
- negative regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of Wnt signaling pathway [TAS]
- positive regulation of activin receptor signaling pathway [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
EIF4EBP1
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO]
- TOR signaling [ISO, ISS]
- insulin receptor signaling pathway [ISO]
- lung development [IEP]
- negative regulation of protein complex assembly [IMP]
- negative regulation of translational initiation [IMP, ISO]
- positive regulation of mitotic cell cycle [ISO]
- response to ethanol [IEP]
- response to ischemia [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes.
PHAS-I is a heat- and acid-stable protein that is phosphorylated on Ser/Thr residues in response to insulin and growth factors. To investigate the phosphorylation of PHAS-I, the protein was expressed in bacteria and purified for use as substrate in protein kinase reactions in vitro. Recombinant PHAS-I was rapidly and stoichiometrically phosphorylated by mitogen-activated protein (MAP) kinase. At saturating MgATP, the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID