BAIT

NFE4

NF-E4
nuclear factor, erythroid 4
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

CLNS1A

CLCI, CLNS1B, ICln
chloride channel, nucleotide-sensitive, 1A
GO Process (4)
GO Function (2)
GO Component (6)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The role of WDR5 in silencing human fetal globin gene expression.

Xu Z, He Y, Ju J, Rank G, Cerruti L, Ma C, Simpson RJ, Moritz RL, Jane SM, Zhao Q

Histone H3 lysine 4 (K4) methylation has been linked with transcriptional activity in mammalian cells. The WD40-repeat protein, WDR5, is an essential component of the MLL complex that induces histone H3 K4 methylation, but the role of WDR5 in human globin gene regulation has not yet been established.To study the role of WDR5 in human globin gene regulation, we performed ... [more]

Haematologica Nov. 01, 2012; 97(11);1632-40 [Pubmed: 22689669]

Throughput

  • Low Throughput

Curated By

  • BioGRID