BAIT

FAM96B

MIP18, CGI-128
family with sequence similarity 96, member B
GO Process (3)
GO Function (1)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

DNAJB6

DJ4, DnaJ, HHDJ1, HSJ-2, HSJ2, LGMD1D, LGMD1E, MRJ, MSJ-1, tcag7.555
DnaJ (Hsp40) homolog, subfamily B, member 6
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

Stehling O, Mascarenhas J, Vashisht AA, Sheftel AD, Niggemeyer B, Roesser R, Pierik AJ, Wohlschlegel JA, Lill R

Numerous cytosolic and nuclear proteins involved in metabolism, DNA maintenance, protein translation, or iron homeostasis depend on iron-sulfur (Fe/S) cofactors, yet their assembly is poorly defined. Here, we identify and characterize human CIA2A (FAM96A), CIA2B (FAM96B), and CIA1 (CIAO1) as components of the cytosolic Fe/S protein assembly (CIA) machinery. CIA1 associates with either CIA2A or CIA2B and the CIA-targeting factor ... [more]

Cell Metab. Aug. 06, 2013; 18(2);187-98 [Pubmed: 23891004]

Throughput

  • High Throughput

Curated By

  • BioGRID