BAIT
TUBG1
CDCBM4, GCP-1, TUBG, TUBGCP1
tubulin, gamma 1
GO Process (4)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
UNC5B
UNC5H2, p53RDL1, RP11-58O1.1
unc-5 homolog B (C. elegans)
GO Process (7)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
- apoptotic process [TAS]
- axon guidance [TAS]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [IMP]
- negative regulation of neuron apoptotic process [IMP]
- positive regulation of apoptotic process [TAS]
- positive regulation of phosphatidylinositol 3-kinase signaling [IMP]
- regulation of apoptotic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.
Centrosome morphology and number are frequently deregulated in cancer cells. Here, to identify factors that are functionally relevant for centrosome abnormalities in cancer cells, we established a protein-interaction network around 23 centrosomal and cell-cycle regulatory proteins, selecting the interacting proteins that are deregulated in cancer for further studies. One of these components, LGALS3BP, is a centriole- and basal body-associated protein ... [more]
Nat Commun Feb. 28, 2013; 4(0);1531 [Pubmed: 23443559]
Throughput
- High Throughput
Curated By
- BioGRID