BAIT
CEP57
MVA2, PIG8, TSP57
centrosomal protein 57kDa
GO Process (5)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZNF385A
HZF, RZF, ZFP385, ZNF385
zinc finger protein 385A
GO Process (8)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [ISS]
- cellular response to DNA damage stimulus [ISS]
- mRNA localization resulting in posttranscriptional regulation of gene expression [ISS]
- megakaryocyte development [ISS]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IMP]
- positive regulation of fat cell differentiation [ISS]
- regulation of cytoplasmic translation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.
Centrosome morphology and number are frequently deregulated in cancer cells. Here, to identify factors that are functionally relevant for centrosome abnormalities in cancer cells, we established a protein-interaction network around 23 centrosomal and cell-cycle regulatory proteins, selecting the interacting proteins that are deregulated in cancer for further studies. One of these components, LGALS3BP, is a centriole- and basal body-associated protein ... [more]
Nat Commun Feb. 28, 2013; 4(0);1531 [Pubmed: 23443559]
Throughput
- High Throughput
Curated By
- BioGRID