BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CUL3
cullin 3
GO Process (21)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- COPII vesicle coating [ISO, ISS]
- ER to Golgi vesicle-mediated transport [ISO, ISS]
- Wnt signaling pathway [ISO]
- cell migration [ISO]
- cell morphogenesis [ISO]
- embryonic cleavage [ISO, ISS]
- gastrulation [ISO]
- in utero embryonic development [ISO]
- integrin-mediated signaling pathway [ISO, ISS]
- mitotic metaphase plate congression [ISO]
- negative regulation of Rho protein signal transduction [ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [ISO]
- positive regulation of cytokinesis [ISO, ISS]
- positive regulation of mitotic metaphase/anaphase transition [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO, ISS]
- protein monoubiquitination [ISO, ISS]
- protein polyubiquitination [ISO, ISS]
- protein ubiquitination [ISO]
- stem cell division [ISO, ISS]
- stress fiber assembly [ISO]
- trophectodermal cellular morphogenesis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID