BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
C1QBP
Habp1, gC1qR
complement component 1, q subcomponent binding protein
GO Process (19)
GO Function (10)
GO Component (7)
Gene Ontology Biological Process
- immune response [TAS]
- mature ribosome assembly [ISO, ISS]
- negative regulation of MDA-5 signaling pathway [ISO, ISS]
- negative regulation of RIG-I signaling pathway [ISO, ISS]
- negative regulation of defense response to virus [ISO, ISS]
- negative regulation of interferon-gamma production [ISO, ISS]
- negative regulation of interleukin-12 production [ISO, ISS]
- negative regulation of mRNA splicing, via spliceosome [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- phosphatidylinositol 3-kinase signaling [ISO, ISS]
- positive regulation of apoptotic process [ISO, ISS]
- positive regulation of cell adhesion [ISO, ISS]
- positive regulation of dendritic cell chemotaxis [ISO, ISS]
- positive regulation of mitochondrial translation [ISO, ISS]
- positive regulation of neutrophil chemotaxis [ISO, ISS]
- positive regulation of protein kinase B signaling [ISO, ISS]
- positive regulation of substrate adhesion-dependent cell spreading [ISO, ISS]
- positive regulation of trophoblast cell migration [ISO, ISS]
- regulation of complement activation [ISO, ISS]
Gene Ontology Molecular Function- adrenergic receptor binding [IDA]
- complement component C1q binding [IDA, ISO]
- hyaluronic acid binding [ISO, ISS]
- kininogen binding [ISO, ISS]
- mRNA binding [ISO, ISS]
- mitochondrial ribosome binding [ISO, ISS]
- protein binding [IPI]
- protein kinase C binding [IDA]
- transcription corepressor activity [ISO, ISS]
- transcription factor binding [ISO]
- adrenergic receptor binding [IDA]
- complement component C1q binding [IDA, ISO]
- hyaluronic acid binding [ISO, ISS]
- kininogen binding [ISO, ISS]
- mRNA binding [ISO, ISS]
- mitochondrial ribosome binding [ISO, ISS]
- protein binding [IPI]
- protein kinase C binding [IDA]
- transcription corepressor activity [ISO, ISS]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID