BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CAMK2B
Ck2b
calcium/calmodulin-dependent protein kinase II beta
GO Process (17)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [ISO]
- activation of meiosis involved in egg activation [ISO]
- calcium ion transport [ISO]
- cell projection morphogenesis [IMP]
- inhibitory G-protein coupled receptor phosphorylation [ISO]
- long-term synaptic potentiation [IMP]
- neuromuscular process controlling balance [ISO]
- peptidyl-serine phosphorylation [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of dendritic spine morphogenesis [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of phospholipase A2 activity [IDA]
- positive regulation of synapse maturation [IMP]
- protein autophosphorylation [ISO, ISS]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of synaptic transmission, cholinergic [ISO]
- response to cadmium ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID