BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
KIF5B
Khc
kinesin family member 5B
GO Process (12)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- axon guidance [IBA]
- cytoplasm organization [ISO]
- metabolic process [IBA, IDA]
- plus-end-directed vesicle transport along microtubule [ISO]
- positive regulation of establishment of protein localization to plasma membrane [ISO]
- positive regulation of potassium ion transport [ISO]
- positive regulation of synaptic transmission, GABAergic [ISO]
- protein localization [IBA]
- regulation of membrane potential [ISO]
- stress granule disassembly [ISO]
- vesicle transport along microtubule [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID