BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
GO Process (9)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IMP, ISO, TAS]
- GTP catabolic process [ISO]
- cardiac muscle cell apoptotic process [IDA]
- cell proliferation [ISO]
- cellular response to hypoxia [IDA]
- phospholipase C-activating G-protein coupled receptor signaling pathway [ISO]
- positive regulation of cytosolic calcium ion concentration [IMP]
- retina development in camera-type eye [ISO]
- sensory perception of taste [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID