BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
MAP1B
Mtap1b
microtubule-associated protein 1B
GO Process (30)
GO Function (5)
GO Component (16)
Gene Ontology Biological Process
- axon extension [ISO]
- axonogenesis [ISO]
- cellular process [ISO]
- cellular response to growth factor stimulus [IEP]
- cellular response to peptide hormone stimulus [IEP]
- dendrite development [ISO]
- developmental maturation [IEP]
- establishment of monopolar cell polarity [ISO]
- induction of synaptic plasticity by chemical substance [IEP]
- microtubule bundle formation [IDA, ISO]
- mitochondrion transport along microtubule [ISO]
- negative regulation of intracellular transport [ISO]
- negative regulation of microtubule depolymerization [IDA]
- nervous system development [IEP]
- neuron development [IEP]
- peripheral nervous system axon regeneration [IEP]
- positive regulation of axon extension [IMP, ISO]
- positive regulation of microtubule polymerization [IDA]
- positive regulation of neuron differentiation [IMP]
- response to axon injury [IEP]
- response to carbohydrate [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to inorganic substance [IEP]
- response to insecticide [IEP]
- response to mechanical stimulus [IEP]
- response to nutrient levels [IEP]
- response to vitamin A [IEP]
- response to wounding [IEP]
- synapse assembly [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [IDA]
- cell [ISO]
- cytoplasm [ISO]
- cytoskeleton [IDA]
- cytosol [ISO]
- dendrite [IDA]
- growth cone [IDA]
- intracellular [ISO]
- microtubule associated complex [IDA]
- neuronal cell body [IDA]
- neuronal postsynaptic density [ISO]
- perikaryon [IDA]
- perinuclear region of cytoplasm [IDA]
- photoreceptor outer segment [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic density [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID