BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
PHB2
Bap, Bap-37, Bap37, Bcap27, Bcap37
prohibitin 2
GO Process (6)
GO Function (0)
GO Component (6)
Gene Ontology Biological Process
- mammary gland alveolus development [ISO]
- mammary gland branching involved in thelarche [ISO]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of mammary gland epithelial cell proliferation [ISO]
- negative regulation of transcription, DNA-templated [ISO, ISS]
- regulation of branching involved in mammary gland duct morphogenesis [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID