BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
SCFD1
RA410, Sly1, rSly1
sec1 family domain containing 1
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [TAS]
- cell morphogenesis [ISS]
- negative regulation of autophagic vacuole assembly [ISO]
- phagocytosis [ISS]
- post-Golgi vesicle-mediated transport [IDA]
- regulation of ER to Golgi vesicle-mediated transport [IMP]
- regulation of protein transport [ISO]
- response to hypoxia [IEP]
- response to toxic substance [ISO]
- retrograde vesicle-mediated transport, Golgi to ER [IMP]
- toxin transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID