BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
USP15
Ubp109
ubiquitin specific peptidase 15
GO Process (9)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- BMP signaling pathway [ISO, ISS]
- histone H2B conserved C-terminal lysine deubiquitination [ISO, ISS]
- monoubiquitinated protein deubiquitination [ISO, ISS]
- pathway-restricted SMAD protein phosphorylation [ISO, ISS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IDA, ISO]
- proteolysis [ISO]
- regulation of proteasomal protein catabolic process [IBA]
- transforming growth factor beta receptor signaling pathway [ISO, ISS]
Gene Ontology Molecular Function
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID