BAIT
STXBP5L
LLGL4
syntaxin binding protein 5-like
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
VIL1
Vil
villin 1
GO Process (19)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- actin filament capping [ISO]
- actin filament depolymerization [ISO]
- actin filament polymerization [ISO]
- actin filament severing [ISO]
- apoptotic process [ISO]
- cellular response to epidermal growth factor stimulus [ISO]
- cellular response to hepatocyte growth factor stimulus [ISO]
- cytoplasmic actin-based contraction involved in cell motility [ISO]
- epidermal growth factor receptor signaling pathway [ISO]
- epithelial cell differentiation [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of actin filament bundle assembly [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of epithelial cell migration [ISO]
- regulation of actin nucleation [ISO]
- regulation of cell shape [ISO]
- regulation of lamellipodium morphogenesis [ISO]
- regulation of wound healing [ISO]
- response to bacterium [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion.
The abundance and functional activity of proteins involved in the formation of the SNARE complex are tightly regulated for efficient exocytosis. Tomosyn proteins are negative regulators of exocytosis. Tomosyn causes an attenuation of insulin secretion by limiting the formation of the SNARE complex. We hypothesized that glucose-dependent stimulation of insulin secretion from β-cells must involve reversing the inhibitory action of ... [more]
J. Biol. Chem. Jul. 07, 2014; 0(0); [Pubmed: 25002582]
Throughput
- High Throughput
Curated By
- BioGRID