The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 4,092 interactions. These additions bring our total number of non-redundant interactions to 471,829 and raw interactions to 681,783. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
Welcome to the Biological General Repository for Interaction Datasets
BioGRID is an online interaction repository with data compiled through comprehensive curation efforts. Our current index is version 3.2.100 and searches 39,991 publications for 681,783 raw protein and genetic interactions from major model organism species. All interaction data are freely provided through our search index and available via download in a wide variety of standardized formats.
Search the BioGRID
Areas of Interest to Help You Get Started
Create custom interaction datasets by protein or by publication. You can also download our entire dataset in a wide variety of standard formats.
Send us your datasets or link to the BioGRID directly from your own website or database. Full details on how to contribute are available here.
We've developed tools that make use of BioGRID data. Check out the list of tools to see if we can help you work with our data.
Find out how many organisms, proteins, publications, and interactions are available in the current release of the BioGRID.
Latest News
The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 29,200 interactions. These additions bring our total number of non-redundant interactions to 469,197 and raw interactions to 677,691. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 10,038 interactions. These additions bring our total number of non-redundant interactions to 452,053 and raw interactions to 648,491. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 15,702 interactions. These additions bring our total number of non-redundant interactions to 444,517 and raw interactions to 638,453. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 60,093 interactions. These additions bring our total number of non-redundant interactions to 432,040 and raw interactions to 622,751. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
The BioGRID‘s curated set of physical and genetic interactions has been updated to include an additional 4,724 interactions. These additions bring our total number of non-redundant interactions to 380,811 and raw interactions to 562,658. New interactions will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these interactions, visit our download page.
The BioGRID was updated today to our newest release designated BioGRID 3.2. This update includes several bug fixes and user interface improvements as well as some new features. The following is a short list of some of the changes:
- Support for Post Translational Modifications. Our result pages may now include listings of post translational modifications. If available, these will be accessible via the “PTM Sites” link in the “Switch View” section of our interaction summaries. Examples: CLA4, CDC28, and SWI4. This feature already includes more than 20,000 PTM sites and downloadable files containing all sites will be made available soon.
- Graphical Viewer. Our search result pages now include a built in graphical viewer. This feature can be accessed by clicking the “Visualize Interactions Graphically” button on any result page.
- Gene Tags. For a given result page, we’ve incorporated gene tags that may contain additional annotation. For instance, genes with new post translational modification data might have a red [P] tag that indicates the existence of phosphorylation sites. Simply mouse over the gene tag for more information. This feature will be greatly expanded in future updates. For a listing of our current tags, visit our wiki.
- Graphical User Interface Updates. We’ve made several user interface updates to improve the functionality of the BioGRID and to reduce page load times.
- Search Improvements. We’ve made several enhancements to improve the speed and accuracy of our search results.
- Compatibility improvements for download files. We’ve fixed several issues with our download files to improve compatibility with standards.
- Updated Wiki Documentation. We’ve updated several pages in our Wiki to provide updated documentation on a variety of topics.
These are just some of the many improvements now available in BioGRID 3.2. We have many additional features already under development for version 3.3 that will expand on this functionality and ensure the BioGRID remains a useful resource for the biological community. If you have any questions about this build or suggestions for future builds, please feel free to contact us at biogridadmin@gmail.com.

Anyone interested in BioGRID updates, changes, and new features, can follow us on Twitter at @biogrid. We will be updating our twitter account regularly, in addition to our standard news feed, so if you want to know about BioGRID status updates as soon as they happen, please be sure to follow us.












