The BioGRID’s curated set of physical and genetic interactions has been updated to include an additional 2,054 interactions. These additions bring our total number of non-redundant interactions to 244,189 and raw interactions to 350,020. New interactions will be added in curation updates on a monthly basis. Please let us know if we have missed or incorrectly reported any interactions by sending an e-mail to biogridadmin@gmail.com.
Welcome to the Biological General Repository for Interaction Datasets
BioGRID is an online interaction repository with data compiled through comprehensive curation efforts. Our current index is version 3.0.68 and searches 23,609 publications for 350,020 raw protein and genetic interactions from major model organism species. All interaction data are freely provided through our search index and available via download in a wide variety of standardized formats.
Search the BioGRID
Search by identifiers, keywords, and gene names...
Areas of Interest to Help You Get Started
Build and Download Interaction Datasets
Create custom interaction datasets by protein or by publication. You can also download our entire dataset in a wide variety of standard formats.
Link To Us or Submit Interactions
Send us your datasets or link to the BioGRID directly from your own website or database. Full details on how to contribute are available here.
Online Tools and Resources
We've developed tools that make use of BioGRID data. Check out the list of tools to see if we can help you work with our data.
View Our Interaction Statistics
Find out how many organisms, proteins, publications, and interactions are available in the current release of the BioGRID.
Latest News
BioGRID Version 3.0.68 Release (2,054 New Physical and Genetic Interactions Added)
Posted: September 1, 2010 - 4:19 am
New Dataset of 748 Interactions from the Harper Group
The BioGRID has posted a new dataset of 748 new physical interactions as reported in Behrends C et al: “Network organization of the human autophagy system (Nature. 2010 Jul 1;466(7302):68-76. PMID: 20562859).” This dataset is available immediately in all BioGRID searches and download files (http://thebiogrid.org/download.php). A special thanks to the authors Behrends C, Sowa ME, Gygi SP, and Harper JW for providing us with the dataset.
If you have an interaction dataset you would like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.
Posted: August 1, 2010 - 6:45 am
BioGRID Version 3.0.67 Release (2,346 New Physical and Genetic Interactions Added)
The BioGRID’s curated set of physical and genetic interactions has been updated to include an additional 2,346 interactions. These additions bring our total number of non-redundant interactions to 243,005 and raw interactions to 347,966. New interactions will be added in curation updates on a monthly basis. Please let us know if we have missed or incorrectly reported any interactions by sending an e-mail to biogridadmin@gmail.com.
Posted: August 1, 2010 - 4:15 am
BioGRID Plugin 2.0.1 Released for Cytoscape
This is a bug-fix release to address the following bugs: 1) allow large lists to be pasted into the filter interface gene and pubmed fields , 2) defect in searching of orf names in tab2 files. To get the plugin please visit our downloads page, http://thebiogrid.org/download.php.
Posted: July 29, 2010 - 1:25 pm
BioGRID Version 3.0.66 Release (3,753 New Physical and Genetic Interactions Added)
The BioGRID’s curated set of physical and genetic interactions has been updated to include an additional 3,753 interactions. These additions bring our total number of non-redundant interactions to 241,173 and raw interactions to 345,620. New interactions will be added in curation updates on a monthly basis. Please let us know if we have missed or incorrectly reported any interactions by sending an e-mail to biogridadmin@gmail.com.
Posted: July 1, 2010 - 6:02 am
New Dataset of 1,912 Saccharomyces cerevisiae Interactions from the Gingras, Nesvizhskii, and Tyers Groups
The BioGRID has posted a new dataset of 1,912 new interactions in Saccharomyces cerevisiae as reported in Breitkreutz A et al: “A global protein kinase and phosphatase interaction network in yeast. (May 2010).” This dataset is available immediately in all BioGRID searches and download files (http://thebiogrid.org/download.php) and is also available in both fully searchable and original file formats with other supplementary information at: www.yeastkinome.org.
To download this dataset directly from the BioGRID visit our associated publication details page. If you have an interaction dataset you would like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.
Posted: June 1, 2010 - 2:21 am
BioGRID Version 3.0.65 Release (3,910 New Physical and Genetic Interactions Added)
The BioGRID’s curated set of physical and genetic interactions has been updated to include an additional 3,910 interactions. These additions bring our total number of non-redundant interactions to 238,339 and raw interactions to 341,867. New interactions will be added in curation updates on a monthly basis. Please let us know if we have missed or incorrectly reported any interactions by sending an e-mail to biogridadmin@gmail.com.
Posted: June 1, 2010 - 12:41 am
BioGRID Plugin 2.0 Released for Cytoscape
BioGRIDPlugin2 is a new plugin for the Cytoscape network visualization tool, designed to allow easy import of interactions from BioGRID data files. An update of our original BioGRIDPlugin, it now allows import of data from our new tab2 file format, filtering of data during import based on gene lists and various interaction attributes, expanding of nodes and saving of networks in tab2 format. For more information, visit the BioGRID Plugin 2.0 entry in our wiki or grab the plugin on our downloads page.
Posted: May 11, 2010 - 10:14 am