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Saccharomyces cerevisiae (S288c)

SSK1

mitogen-activated protein kinase kinase kinase SSK1, L000002084, YLR006C

Cytoplasmic phosphorelay intermediate osmosensor and regulator; part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; required for mitophagy; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate

Kinome Project (Sc)

GO Process (4)

GO Function (4)

GO Component (1)

Gene Ontology Biological Process

activation of MAPKKK activity involved in osmosensory signaling pathway [IGI, IMP]

osmosensory signaling via phosphorelay pathway [IDA]

positive regulation of actin cytoskeleton reorganization [IMP]

positive regulation of protein autophosphorylation [IDA]

Gene Ontology Molecular Function

mitogen-activated protein kinase kinase kinase binding [IPI]
phosphorelay response regulator activity [IMP]
protein homodimerization activity [IDA]
protein kinase activator activity [IDA, IMP]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31279

559292

Interactors 146
Interactions 230
Network
PTM Sites 21