Saccharomyces cerevisiae (S288c)

KAE1

YKR038C

Highly conserved ATPase of HSP70/DnaK family; essential functional component of the EKC/KEOPS complex, with Bud32p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription

Kinome Project (Sc)

GO Process (6)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

chromosome organization [IMP]

positive regulation of transcription from RNA polymerase II promoter [IPI]

tRNA modification [IDA]

telomere maintenance [IPI]

telomere maintenance via recombination [IGI, IMP]

threonylcarbamoyladenosine metabolic process [IMP]

Gene Ontology Molecular Function

chromatin DNA binding [IDA]

Gene Ontology Cellular Component

EKC/KEOPS complex [IDA]

cytoplasm [IDA]

nuclear chromatin [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34169

559292

Interactors 176
Interactions 213
Network
PTM Sites 1